Umbilical cord blood banking is a relatively new procedure that can save lives. Cord blood contains stem cells which can be frozen for later use in medical therapies, such as stem cell transplantation or regenerative medicine.The term “cord blood” is used for blood that is drawn from the umbilical cord and the placenta after a baby is born. Up until recently this afterbirth was discarded as medical waste.For a comprehensive list of diseases for which transplants of blood-forming stem cells are a standard treatment as well as of therapies in clinical trials and experimental treatments, please consult the website of Parents’ Guide to Cord Blood Foundation available here.
Proposed classification of haematopoietic stem cell transplantation procedures in children
|Sibling donor||Well-matched unrelated donor||Mismatched unrelated donor|
|Acute lymphoblastic leukaemia (ALL)||S||S||CO||CO|
|Acute myeloid leukaemia (AML)||S||S||CO||CO|
|Chronic myeloid leukemia (CML)||S||S||D||GNR|
|Non-Hodgkin Lymphoma (NHL)||S||CO||GNR||CO|
|MPS - 1 H E. Hurler||S||S||CO||NA|
|MPS VI Maroteaux Lamy||CO||CO||CO||NA|
|Blackfan Diamond anaemia||S||CO||GNR||NA|
|Sickle cell disease||S||CO||GNR||NA|
|Chronic granulomatous disease||S||S||CO||NA|
|Germ cell tumour||GNR||GNR||GNR||CO|
|Soft tissue sarcoma||D||D||GNR||CO|
Proposed classification of transplant procedures for adults 2010
|Sibling donor||Well-matched unrelated donor||Mismatchedunrelated donor|
|Acute myeloid leukaemia (AML)||S||CO||D||CO|
|Acute lymphoblastic leukaemia (ALL)||S||S||CO||D|
|Chronic myeloid leukaemia (CML)||S||S||CO||D|
|Chronic lymphocytic leukaemia (CLL)||S||S||D||CO|
|Diffuse large B-cell lymphoma||CO||CO||GNR||CO|
|Mantle cell lymphoma||CO||D||GNR||S|
|Lymphoblastic lymphoma and Burkitts lymphoma||CO||CO||GNR||CO|
|Follicular B-cell Non-Hodgkin Lymphoma||CO||CO||GNR||CO|
|T cell Non-Hodgkin Lymphoma||D||GNR||CO|
|Lymphocyte predominant nodular Hodgkin lymphoma||GNR||GNR||GNR||CO|
|Severe aplastic anemia||S||CO||CO||GNR|
|Paroxysmal nocturnal haemoglobinuria||S||CO||CO||GNR|
|Germ cell tumours||GNR||GNR||GNR||CO|
|Medulloblastoma||GNR||GNR||GNR||D / CO|
|Small cell lung cancer||GNR||GNR||GNR||D|
|Renal cell carcinoma||CO||CO||GNR||GNR|
|Soft cell sarcoma||D||GNR||GNR||D|
|Systemic lupus erythromatosis||D||GNR||GNR||CO|
|Chronic inflammatory demyelinating polyradiculoneuropathy||GNR||GNR||GNR||D|
This classification does not cover patients for whom a syngeneic donor is available S standard of care, generaly indicated in suitable patients; CO clinical option, can be carried out, but after careful assesment of risks and benefits; D developmental, further trials are needed; GNR generally not recommended; NA not applicable
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